CIDeRplusGeneral Information:
| Id: | 427 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mus musculus | |
| BTO:0000165 C2C12 cell | |
| article | |
| Reference: | Lee HK et al.(2009) The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid Mol. Biol. Cell 20: 1533-1544 [PMID: 19144826] |
Interaction Information:
| Comment | The stimulated activity of Akt1 on the GSK substrate is markedly inhibited in the presence of intracellular beta-amyloid42. |
|
Formal Description Interaction-ID: 2001 |
gene/protein decreases_activity of gene/protein |
| Drugbank entries | Show/Hide entries for AKT1 |