General Information:

Id: 4,133
Diseases: Neurological
Rattus norvegicus
male
article
Reference: Clark KA et al.(2006) Effects of central and systemic administration of leptin on neurotransmitter concentrations in specific areas of the hypothalamus Am. J. Physiol. Regul. Integr. Comp. Physiol. 290: R306-R312 [PMID: 16210420]

Interaction Information:

Comment Leptin treatment decreased dopamine concentrations significantly in the paraventricular nucleus.
Formal Description
Interaction-ID: 42564

gene/protein

LEP

decreases_quantity of

drug/chemical compound

Dopamine

in the paraventricular nucleus
Drugbank entries Show/Hide entries for
Comment Serotonin (5-HT) concentration decreased significantly in the paraventricular nucleus after both intraperitoneal and intracerebroventricular injections of leptin and decreased in the ventromedial hypothalamus only with intracerebroventricular treatment of leptin.
Formal Description
Interaction-ID: 42565

gene/protein

LEP

decreases_quantity of

drug/chemical compound

Serotonin

in the paraventricular nucleus