CIDeRplusGeneral Information:
| Id: | 4,118 (click here to show other Interactions for entry) |
| Diseases: |
Multiple sclerosis
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | Arnason BG et al.(2013) Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis Mult. Scler. 19: 130-136 [PMID: 23034287] |
Interaction Information:
| Comment | NA modulates inflammation and protects against EAE, suggesting that melanocortin-induced NA release may be relevant in MS, a notion reinforced by findings with the beta2-adrenergic agonist albuterol which, as an add-on to glatiramer acetate, strikingly reduces MS relapses. |
|
Formal Description Interaction-ID: 42567 |
drug/chemical compound decreases_activity of phenotype experimental autoimmune encephalomyelitis |