Arnason BG et al.(2013) Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis Mult. Scler. 19: 130-136
[PMID: 23034287]
Interaction Information:
Comment
NA modulates inflammation and protects against EAE, suggesting that melanocortin-induced NA release may be relevant in MS, a notion reinforced by findings with the beta2-adrenergic agonist albuterol which, as an add-on to glatiramer acetate, strikingly reduces MS relapses.