General Information:

Id: 4,112
Diseases: Neurological
Rattus norvegicus
article
Reference: Zhu HJ and Liu GQ(2004) Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism Life Sci. 75: 1313-1322 [PMID: 15234189]

Interaction Information:

Comment The level of P-gp expression significantly increased in rat brain microvessel endothelial cells after the treatment of 100 microM glutamate by an NMDA receptor-mediated mechanism.
Formal Description
Interaction-ID: 42403

drug/chemical compound

Glutamate

increases_quantity of

gene/protein

ABCB1

in brain microvessel
Drugbank entries Show/Hide entries for ABCB1