CIDeRplusGeneral Information:
| Id: | 3,954 |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
| Homo sapiens | |
| female | |
| African Americans | |
| article | |
| Reference: | Fiehn O et al.(2010) Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women PLoS ONE 5 [PMID: 21170321] |
Interaction Information:
| Comment | In non-diabetic persons harboring the missense g/a UCP3 allele, concentrations of 2-oxoglutarate (alpha-ketoglutarate) and glutamate were both reduced. |
|
Formal Description Interaction-ID: 40132 |
SNP affects_quantity of drug/chemical compound |
| Comment | In non-diabetic persons harboring the missense g/a UCP3 allele, concentrations of 2-oxoglutarate (alpha-ketoglutarate) and glutamate were both reduced. |
|
Formal Description Interaction-ID: 40134 |
SNP affects_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of 3-hydroxybutanoic acid (beta-hydroxybutryrate) was increased. |
|
Formal Description Interaction-ID: 40135 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of oleic acid was increased. |
|
Formal Description Interaction-ID: 40137 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of gluconic acid was increased. |
|
Formal Description Interaction-ID: 40138 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of fructose was increased. |
|
Formal Description Interaction-ID: 40139 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of palmitoleic acid was increased. |
|
Formal Description Interaction-ID: 40140 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of 3,6-anhydrogalactose was increased. |
|
Formal Description Interaction-ID: 40141 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of glucuronic acid was increased. |
|
Formal Description Interaction-ID: 40142 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of glucose was increased. |
|
Formal Description Interaction-ID: 40143 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of heptadecanoic acid was increased. |
|
Formal Description Interaction-ID: 40144 |
disease increases_quantity of drug/chemical compound Heptadecanoic acid |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of inulobiose was increased. |
|
Formal Description Interaction-ID: 40146 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of leucine was increased. |
|
Formal Description Interaction-ID: 40147 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of 2-hydroxybutanoic acid (alpha-hydroxybutryrate) was increased. |
|
Formal Description Interaction-ID: 40148 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of 2-deoxyerythritol was increased. |
|
Formal Description Interaction-ID: 40149 |
disease increases_quantity of drug/chemical compound 2-Deoxyerythritol |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of palmitic acid was increased. |
|
Formal Description Interaction-ID: 40152 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of 2-ketoisocaproic acid (alpha-ketoisocaproate) was increased. |
|
Formal Description Interaction-ID: 40153 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of uridine was increased. |
|
Formal Description Interaction-ID: 40155 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of cystine was increased. |
|
Formal Description Interaction-ID: 40156 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of xylose was increased. |
|
Formal Description Interaction-ID: 40158 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of histidine was increased. |
|
Formal Description Interaction-ID: 40159 |
disease increases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of stearic acid was increased. |
|
Formal Description Interaction-ID: 40160 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of benzylalcohol was decreased. |
|
Formal Description Interaction-ID: 40161 |
disease decreases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of benzoic acid was decreased. |
|
Formal Description Interaction-ID: 40162 |
disease decreases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of lysine was decreased. |
|
Formal Description Interaction-ID: 40163 |
disease decreases_quantity of drug/chemical compound |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of ethanolamine was decreased. |
|
Formal Description Interaction-ID: 40164 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of arachidonic acid was decreased. |
|
Formal Description Interaction-ID: 40165 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of glycine was decreased. |
|
Formal Description Interaction-ID: 40166 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The study revealed identifiable plasma metabolites with significantly-altered concentrations in obese non-diabetic vs. type 2 diabetic African-American women. In diabetic women the plasma concentration of glycerol-3-phosphate (glycerol-alpha-phosphate) was decreased. |
|
Formal Description Interaction-ID: 40167 |
disease decreases_quantity of drug/chemical compound |