CIDeRplusGeneral Information:
| Id: | 385 (click here to show other Interactions for entry) |
| Diseases: |
Amyotrophic lateral sclerosis
|
| Homo sapiens | |
| BTO:0003350 BV-2 cell | |
| article | |
| Reference: | Liu Y et al.(2009) Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2 J. Biol. Chem. 284: 3691-3699 [PMID: 19091752] |
Interaction Information:
| Comment | P47-PHOX mediates SOD1 G93A mutation-enhanced oxidative stress and subsequent TNF-alpha secretion following TLR2 stimulation. |
|
Formal Description Interaction-ID: 1595 |
gene/protein affects_activity of process |