CIDeRplusGeneral Information:
| Id: | 3,846 |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Homo sapiens | |
| male | |
| article | |
| Reference: | Chorell E et al.(2009) Predictive metabolomics evaluation of nutrition-modulated metabolic stress responses in human blood serum during the early recovery phase of strenuous physical exercise J. Proteome Res. 8: 2966-2977 [PMID: 19317510] |
Interaction Information:
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
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Formal Description Interaction-ID: 38591 |
environment low carbohydrate beverage intake following exercise increases_quantity of complex/PPI Insulin |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
|
Formal Description Interaction-ID: 38592 |
environment high carbohydrate beverage intake following exercise increases_quantity of complex/PPI Insulin |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
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Formal Description Interaction-ID: 38593 |
environment low carbohydrate-protein beverage intake following exercise increases_quantity of complex/PPI Insulin |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
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Formal Description Interaction-ID: 38594 |
environment water intake following exercise NOT increases_quantity of complex/PPI Insulin |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
|
Formal Description Interaction-ID: 38595 |
environment low carbohydrate beverage intake following exercise increases_quantity of drug/chemical compound |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
|
Formal Description Interaction-ID: 38596 |
environment high carbohydrate beverage intake following exercise increases_quantity of drug/chemical compound |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
|
Formal Description Interaction-ID: 38597 |
environment low carbohydrate-protein beverage intake following exercise increases_quantity of drug/chemical compound |
| Comment | As expected, an intake of low (LCHO) and high carbohydrate (HCHO) and carbohydrate-protein beverage (LCHO-P) following exercise resulted in a macronutrient related elevation of insulin and glucose compared to the sole ingestion of water. |
|
Formal Description Interaction-ID: 38598 |
environment water intake following exercise NOT increases_quantity of drug/chemical compound |
| Comment | An apparent decline of free fatty acids (FFA), occurring 15 min after macronutrient intake, was seen. |
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Formal Description Interaction-ID: 38599 |
environment low carbohydrate beverage intake following exercise increases_activity of |
| Comment | An apparent decline of free fatty acids (FFA), occurring 15 min after macronutrient intake, was seen. |
|
Formal Description Interaction-ID: 38600 |
environment high carbohydrate beverage intake following exercise increases_activity of |
| Comment | An apparent decline of free fatty acids (FFA), occurring 15 min after macronutrient intake, was seen. |
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Formal Description Interaction-ID: 38601 |
environment low carbohydrate-protein beverage intake following exercise increases_activity of |
| Comment | The constant high concentration of FFA throughout the recovery period in subjects ingesting water indicates a continuous catabolic state compared to the FFA response in subjects ingesting protein and/or carbohydrates. |
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Formal Description Interaction-ID: 38602 |
environment water intake following exercise increases_activity of |
| Comment | The constant high concentration of FFA throughout the recovery period in subjects ingesting water indicates a continuous catabolic state compared to the FFA response in subjects ingesting protein and/or carbohydrates. |
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Formal Description Interaction-ID: 38603 |
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| Comment | Subjects ingesting low carbohydrate-protein beverage (LCHO-P) showed a decrease in 3-methylhistidine (3-MeHis), a urinary marker for protein (myofibrillar) breakdown and an increase in pseudouridine (PSU), a modified nucleoside, compared to the sole ingestion of carbohydrate or water. |
|
Formal Description Interaction-ID: 38604 |
environment low carbohydrate-protein beverage intake following exercise decreases_quantity of drug/chemical compound |
| Comment | Subjects ingesting low carbohydrate-protein beverage (LCHO-P) showed a decrease in 3-methylhistidine (3-MeHis), a urinary marker for protein (myofibrillar) breakdown and an increase in pseudouridine (PSU), a modified nucleoside, compared to the sole ingestion of carbohydrate or water. |
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Formal Description Interaction-ID: 38972 |
environment low carbohydrate-protein beverage intake following exercise increases_quantity of drug/chemical compound |
| Comment | The ingestion of low carbohydrate-protein beverage (LCHO-P) produced an increase in cholesterol (Chol) and 4-deoxyerythronic acid (4-DEA). |
|
Formal Description Interaction-ID: 38973 |
environment low carbohydrate-protein beverage intake following exercise increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The ingestion of low carbohydrate-protein beverage (LCHO-P) produced an increase in cholesterol (Chol) and 4-deoxyerythronic acid (4-DEA). |
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Formal Description Interaction-ID: 38974 |
environment low carbohydrate-protein beverage intake following exercise increases_quantity of drug/chemical compound 4-Deoxyerythronic acid |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
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Formal Description Interaction-ID: 38975 |
environment water intake following exercise NOT increases_quantity of drug/chemical compound |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38976 |
environment water intake following exercise increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38977 |
environment water intake following exercise increases_quantity of drug/chemical compound |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38978 |
environment low carbohydrate beverage intake following exercise decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38979 |
environment high carbohydrate beverage intake following exercise decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38980 |
environment water intake following exercise NOT decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | Other interesting findings were metabolites which deviated from their general class response, that is, suberic acid (SuA), a dicarboxylic fatty acid, and glycine (Gly), a common amino acid which acts as an inhibitory neurotransmitter. SuA did not increase after ingesting water, compared to the ingestion of macronutrients, in comparison with other fatty acids, for example, arachidonic acid (AA) and linoleic acid (LA). In addition, the Gly concentration, as compared to general amino acids, decreased when ingesting carbohydrate beverages, that is, LCHO and HCHO, which was not observed when ingesting water and LCHO-P. |
|
Formal Description Interaction-ID: 38981 |
environment low carbohydrate-protein beverage intake following exercise NOT decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | Pseudouridine was suggested as a novel marker for pro-anabolic effect following LCHO-P ingestion, which was supported by the detected decrease of the catabolic marker 3-methylhistidine. |
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Formal Description Interaction-ID: 38982 |
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| Comment | Pseudouridine was suggested as a novel marker for pro-anabolic effect following LCHO-P ingestion, which was supported by the detected decrease of the catabolic marker 3-methylhistidine. |
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Formal Description Interaction-ID: 38983 |
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