General Information:

Id: 3,792 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Srikanth V et al.(2011) Advanced glycation endproducts and their receptor RAGE in Alzheimers disease Neurobiol. Aging 32: 763-777 [PMID: 19464758]

Interaction Information:

Comment Although many epidemiological studies suggest that there is a connection between antioxidants and a reduced risk of AD, only a few trials with single antioxidants including Vitamin E, estrogen, and alpha-lipoic acid have displayed some benefits for AD patients, suggesting that these drugs are only effective in very early stages of the disease.
Formal Description
Interaction-ID: 38232

drug/chemical compound

Lipoate

decreases_activity of

probabely only effective in very early stages of the disease