General Information:

Id: 3,562 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Bao Y et al.(2009) Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers J. Proteome Res. 8: 1623-1630 [PMID: 19714868]

Interaction Information:

Comment All of the three treatments were able to down-regulate the high level of glutamate to a lower level in serum, suggesting a possible effect on prevention and amelioration of diabetic complications in T2DM patients, since it has been reported that a high level of serum glutamate is involved in immunodeficiency, amyotrophic lateral sclerosis, and neurological complications.
Formal Description
Interaction-ID: 33211

drug/chemical compound

Repaglinide

decreases_quantity of

drug/chemical compound

Glutamate

in blood serum; in diabetic patients
Drugbank entries Show/Hide entries for Repaglinide