CIDeRplusGeneral Information:
| Id: | 339 |
| Diseases: |
Status epilepticus
|
| Rattus norvegicus | |
| BTO:0000601 hippocampus | |
| article | |
| Reference: | de Freitas RL et al.(2010) Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone Brain Res. Bull. 81: 505-509 [PMID: 19800952] |
Interaction Information:
| Comment | The oxidative stress in rat hippocampus was induced by pilocarpine. There was a significant increase in lipid peroxidation and nitrite levels in pilocarpine group. |
|
Formal Description Interaction-ID: 1333 |
drug/chemical compound increases_activity of process |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Buspirone exerted anticonvulsant effects associated with the inhibition of the development of oxidative stress. |
|
Formal Description Interaction-ID: 1334 |
drug/chemical compound decreases_activity of process |
| Comment | The oxidative stress in rat hippocampus was induced by pilocarpine. There was a significant increase in lipid peroxidation and nitrite levels in pilocarpine group. |
|
Formal Description Interaction-ID: 13705 |
process increases_quantity of drug/chemical compound |
| Comment | The oxidative stress in rat hippocampus was induced by pilocarpine. There was a significant increase in lipid peroxidation and nitrite levels in pilocarpine group. |
|
Formal Description Interaction-ID: 13706 |
process increases_activity of process |