General Information:

Id: 3,388 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Carnitine deficiency, systemic primary - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Status epilepticus
Mammalia
review
Reference: Ringseis R et al.(2012) Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency Eur J Nutr 1: 1-18 [PMID: 22134503]

Interaction Information:

Comment Valproic acid contributes to carnitine deficiency through decreasing the concentration of alpha-ketoglutarate that is required for de novo biosynthesis of carnitine.
Formal Description
Interaction-ID: 31814

drug/chemical compound

Valproic acid

decreases_quantity of

drug/chemical compound

2-Oxoglutarate

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