General Information:

Id: 335
Diseases: Epilepsy, temporal lobe
Status epilepticus
Rattus norvegicus
BTO:0001066 hippocampal pyramidal layer
article
Reference: Lopez-Meraz ML et al.(2010) Vulnerability of postnatal hippocampal neurons to seizures varies regionally with their maturational stage. Neurobiol. Dis. 37: 394-402 [PMID: 19879360]

Interaction Information:

Comment The caspase-8 and caspase-3, but not caspase-9, are up-regulated in lithium-pilocarpine model of status epilepticus in 14 days old rat pups.
Formal Description
Interaction-ID: 1316

drug/chemical compound

Pilocarpine

affects_activity of

gene/protein

CASP8

in pilocarpine rat model
Drugbank entries Show/Hide entries for Pilocarpine
Comment The caspase-8 and caspase-3, but not caspase-9, are up-regulated in lithium-pilocarpine model of status epilepticus in 14 days old rat pups.
Formal Description
Interaction-ID: 1317

drug/chemical compound

Pilocarpine

affects_activity of

gene/protein

CASP3

in pilocarpine rat model
Drugbank entries Show/Hide entries for Pilocarpine or CASP3
Comment The caspase-8 and caspase-3, but not caspase-9, are up-regulated in lithium-pilocarpine model of status epilepticus in 14 days old rat pups.
Formal Description
Interaction-ID: 1318

drug/chemical compound

Pilocarpine

NOT affects_activity of

gene/protein

CASP9

in pilocarpine rat model
Drugbank entries Show/Hide entries for Pilocarpine