CIDeRplusGeneral Information:
| Id: | 310 (click here to show other Interactions for entry) |
| Diseases: |
Amyotrophic lateral sclerosis
|
| Mus musculus | |
| SOD1 wt or SOD1G93A or SOD1G85R transgenic mouse, transfected with human wt SOD1 or human SOD1G93A or human SOD1G85R | |
| BTO:0000312 motoneuron | |
| article | |
| Reference: | Raoul C et al.(2006) Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL Proc. Natl. Acad. Sci. U.S.A. 103: 6007-6012 [PMID: 16581901] |
Interaction Information:
| Comment | NO leads to death of mutant, but not control, motoneurons. |
|
Formal Description Interaction-ID: 1232 |
drug/chemical compound increases_activity of process |