General Information:

Id: 3,081 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0003704 H4 neuroglioma cell
article
Reference: Samy AS and Igwe OJ(2012) Regulation of IL-1beta-induced cyclooxygenase-2 expression by interactions of Abeta peptide, apolipoprotein E and nitric oxide in human neuroglioma J. Mol. Neurosci. 47: 533-545 [PMID: 22101739]

Interaction Information:

Comment Increased PGE2 resulted from increased nitrosative stress, which is enhanced by apoE4.
Formal Description
Interaction-ID: 28341

gene/protein mutant

APOE (isoform E4)

increases_activity of

process

response to nitrosative stress