CIDeRplusGeneral Information:
| Id: | 3,001 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Mus musculus | |
| article | |
| Reference: | Petersen HV et al.(2000) Pax4 represses pancreatic glucagon gene expression. Mol. Cell Biol. Res. Commun. 3: 249-254 [PMID: 10891400] |
Interaction Information:
| Comment | Pax4 is able to dose dependently repress transcription of the glucagon promoter to less than 50%, whereas addition of Nkx6.1 has no effect. |
|
Formal Description Interaction-ID: 27331 |
|
| Comment | Pax4 inhibits insulin gene regulation. |
|
Formal Description Interaction-ID: 27333 |
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| Drugbank entries | Show/Hide entries for INS |