General Information:

Id: 2,966 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
MODY, type IV - [OMIM]
Mus musculus
article
Reference: Sachdeva MM et al.(2009) Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress Proc. Natl. Acad. Sci. U.S.A. 106 [PMID: 19855005]

Interaction Information:

Comment In islets isolated from 8- to 12-week-old Pdx1+/- mice eight genes were downregulated: Mafa, Slc2a2 (also known as Glut2), Pax4, Mitf, Lrp2, Nnat, Ero1lb, and Setd5.
Formal Description
Interaction-ID: 27035

gene/protein

PDX1

affects_expression of

gene/protein

PAX4

in pancreas, in pancreatic islets