General Information:

Id: 275
Diseases: Amyotrophic lateral sclerosis
Mus musculus
BTO:0001279 spinal cord
article
Reference: Kieran D et al.(2008) Control of motoneuron survival by angiogenin J. Neurosci. 28 [PMID: 19109488]

Interaction Information:

Comment Angiogenin had a direct protective effect on motoneurons.
Formal Description
Interaction-ID: 1115

gene/protein

ANG

decreases_activity of

phenotype

motor neuron degeneration

Drugbank entries Show/Hide entries for ANG
Comment Treatment of motoneurons with angiogenin for 3 hours showed an activation of Akt-1.
Formal Description
Interaction-ID: 1117

gene/protein

ANG

increases_activity of

gene/protein

AKT1

Drugbank entries Show/Hide entries for ANG or AKT1