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Field	Query

	Field	Term

General Information:

Id:	2,072 (click here to show other Interactions for entry)
Diseases:	Alzheimer disease - [OMIM]
Organism:	Mus musculus
Organism Model:	ApoE4 mouse
Publication type:	article
Reference:	Shenk JC et al.(2009) The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimers disease J. Neurol. Sci. 283: 199-206 [PMID: 19342064]

Interaction Information:

Comment	Compared to WT mice, CBF (cerebral blood flow) was significantly lower in ApoE4 6-month and 12-month mice.
Formal Description Interaction-ID: 16716	gene/protein mutant APOE (isoform E4) increases_activity of phenotype decreased cerebral blood flow rate in ApoE4 6-month and 12-month mice; compared to WT mouse

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