CIDeRplusGeneral Information:
| Id: | 1,893 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | Vance JE and Hayashi H(2010) Formation and function of apolipoprotein E-containing lipoproteins in the nervous system Biochim. Biophys. Acta 1801: 806-818 [PMID: 20170744] |
Interaction Information:
| Comment | Individuals with one APOE4 isoform are 3 to 4 times as likely to develop AD as those without any APOE4, and people with two APOE4 alleles have a 12-fold higher risk of developing AD. |
|
Formal Description Interaction-ID: 14500 |
|