Wang J et al.(2009) 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria J. Biol. Chem. 284
[PMID: 19289463]
Interaction Information:
Comment
Co-immunoprecipitation of 14-3-3 brings down phosphorylated TH in MN9D cells.
Knockdown of 14-3-3zeta but not 14-3-3eta reduced the levels of DOPA and DA in MN9D cells, suggesting the possibility that an interaction between 14-3-3zeta and TH physiologically contributes to DA synthesis in midbrain dopaminergic neuronal cells.
Knockdown of 14-3-3zeta but not 14-3-3eta reduced the levels of DOPA and DA in MN9D cells, suggesting the possibility that an interaction between 14-3-3zeta and TH physiologically contributes to DA synthesis in midbrain dopaminergic neuronal cells.