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General Information:
Id:
13,394
Diseases:
Ciliopathy
Canis lupus familiaris
article
Reference:
Zhang MZ et al.(2004) PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells Proc Natl Acad Sci U S A 101: 2311-2316
[PMID: 14983006]
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Comment
Polycystin-2, a gene product associated with autosomal dominant polycystic disease, has been well-documented to localize at the primary cilium of renal cultured cell lines and tissues. PKHD1 was colocalized with polycystin-2 at the basal bodies / primary cilia in MDCK cells.
Polycystin-2, a gene product associated with autosomal dominant polycystic disease, has been well-documented to localize at the primary cilium of renal cultured cell lines and tissues. PKHD1 was colocalized with polycystin-2 at the basal bodies / primary cilia in MDCK cells.
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