General Information:

Id: 1,184 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Chronic granulomatous disease
Mammalia
review
Reference: Wilkinson BL and Landreth GE(2006) The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimers disease J Neuroinflammation 3: 30 [PMID: 17094809]

Interaction Information:

Comment The source of fibrillar beta-amyloid induced reactive oxygen species is primarily the microglial nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.
Formal Description
Interaction-ID: 7859

complex/PPI

Amyloid beta peptide (fibrillar)

increases_quantity of

drug/chemical compound

Reactive oxygen species