General Information:

Id: 11,849 (click here to show other Interactions for entry)
Diseases: SARS-CoV infection
Homo sapiens
HEK-ACE2 cells; Huh7 cells
article
Reference: Lambert DW et al.(2008) Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain FEBS Lett. 582: 385-390 [PMID: 18070603]

Interaction Information:

Comment Angiotensin-converting enzyme-2 (ACE2) is a regulatory protein of the renin-angiotensin system (RAS) and a receptor for the causative agent of severe-acute respiratory syndrome (SARS), the SARS-coronavirus. Calmodulin associates with ACE2 and that this interaction is decreased by calmodulin inhibitors.
Formal Description
Interaction-ID: 116999

gene/protein

Calmodulin

interacts (colocalizes) with

gene/protein

ACE2

decreased by calmodulin inhibitors
Drugbank entries Show/Hide entries for ACE2