General Information:

Id: 11,758 (click here to show other Interactions for entry)
Diseases: Pulmonary fibrosis, idiopathic - [OMIM]
Homo sapiens
article
Reference: Shao M et al.(2019) Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-beta1 in alveolar epithelial cells Biomed. Pharmacother. 117 [PMID: 31387171]

Interaction Information:

Comment TGF-beta1 treatment downregulated the mRNA and protein expression of ACE2 in a time-dependent manner in A549 cells through inhibiting SIRT1.
Formal Description
Interaction-ID: 116457

gene/protein

TGFB1

decreases_expression of

gene/protein

ACE2

in A549 cells; via inhibiting SIRT1 expression
Drugbank entries Show/Hide entries for TGFB1 or ACE2