CIDeRplusGeneral Information:
| Id: | 11,748 (click here to show other Interactions for entry) |
| Diseases: |
COVID-19
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| Homo sapiens | |
| review | |
| Reference: | Sriram K and Insel PA(2020) A hypothesis for pathobiology and treatment of COVID-19: The centrality of ACE1/ACE2 imbalance Br J Pharmacol 177: 4825-4844 [PMID: 32333398] |
Interaction Information:
| Comment | ANG II is cleaved by multiple enzymes, e.g. prolyl endopeptidase (PREP), but most importantly ACE2, to form ANG (1-7). ANG II also forms ANG IV via the action of aminopeptidases. |
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Formal Description Interaction-ID: 116370 |
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| Drugbank entries | Show/Hide entries for ACE2 |