General Information:

Id: 116 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Alessi DR et al.(1996) Mechanism of activation of protein kinase B by insulin and IGF-1 EMBO J. 15: 6541-6551 [PMID: 8978681]

Interaction Information:

Comment After transfection into 293 cells AKT1 was activated 20- and 50-fold in response to insulin and IGF-1 respectively.
Formal Description
Interaction-ID: 391

gene/protein

IGF1

increases_activity of

gene/protein

AKT1

Drugbank entries Show/Hide entries for IGF1 or AKT1