General Information:

Id: 1,115 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Rattus norvegicus
6-OHDA-induced PD rat model
BTO:0000143 substantia nigra
article
Reference: Hu LF et al.(2010) Neuroprotective effects of hydrogen sulfide on Parkinsons disease rat models. Aging Cell 9: 135-146 [PMID: 20041858]

Interaction Information:

Comment NaHS treatment inhibited microglial activation in the SN and accumulation of pro-inflammatory factors (e.g. TNF-alpha and nitric oxide) in the striatum via NF-kappaB pathway.
Formal Description
Interaction-ID: 7168

drug/chemical compound

NaHS

decreases_quantity of

drug/chemical compound

NO

in striatum; via NF-kappaB pathway