CIDeRplusGeneral Information:
| Id: | 1,110 |
| Diseases: |
Epilepsy, temporal lobe
Status epilepticus |
| Rattus norvegicus | |
| Sprague‚ÄďDawley rats | |
| BTO:0002701 brain | |
| article | |
| Reference: | Voutsinos-Porche B et al.(2004) Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy. Neurobiol. Dis. 17: 385-402 [PMID: 15571975] |
Interaction Information:
| Comment | The immunohistochemical expression of IL1-beta, NF-kappaB, and COX-2 started by 12 h post-injection, persisted for 24 h (status epilepticus period), and returned to basal levels by 3 and 6 days (latent period) in lithium-pilocarpine model of temporal lobe epilepsy. |
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Formal Description Interaction-ID: 7114 |
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| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The immunohistochemical expression of IL1-beta, NF-kappaB, and COX-2 started by 12 h post-injection, persisted for 24 h (status epilepticus period), and returned to basal levels by 3 and 6 days (latent period) in lithium-pilocarpine model of temporal lobe epilepsy. |
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Formal Description Interaction-ID: 7115 |
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| Drugbank entries | Show/Hide entries for IL1B |
| Comment | The immunohistochemical expression of IL1-beta, NF-kappaB, and COX-2 started by 12 h post-injection, persisted for 24 h (status epilepticus period), and returned to basal levels by 3 and 6 days (latent period) in lithium-pilocarpine model of temporal lobe epilepsy. |
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Formal Description Interaction-ID: 7116 |
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| Drugbank entries | Show/Hide entries for NFKB1 |
| Comment | The immunohistochemical expression of IL1-beta, NF-kappaB, and COX-2 started by 12 h post-injection, persisted for 24 h (status epilepticus period), and returned to basal levels by 3 and 6 days (latent period) in lithium-pilocarpine model of temporal lobe epilepsy. |
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Formal Description Interaction-ID: 7117 |
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| Drugbank entries | Show/Hide entries for PTGS2 |
| Comment | IL1-B expression was found in glial cells, COX-2 expression in neurons, and NF-KB in both cell types. |
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Formal Description Interaction-ID: 7118 |
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| Drugbank entries | Show/Hide entries for IL1B |
| Comment | IL1-B expression was found in glial cells, COX-2 expression in neurons, and NF-KB in both cell types. |
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Formal Description Interaction-ID: 7119 |
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| Drugbank entries | Show/Hide entries for PTGS2 |
| Comment | IL1-B expression was found in glial cells, COX-2 expression in neurons, and NF-KB in both cell types. |
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Formal Description Interaction-ID: 7120 |
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| Drugbank entries | Show/Hide entries for NFKB1 |
| Comment | IL1-B expression was found in glial cells, COX-2 expression in neurons, and NF-KB in both cell types. |
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Formal Description Interaction-ID: 7121 |
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| Drugbank entries | Show/Hide entries for NFKB1 |