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Field	Query

	Field	Term

General Information:

Id:	10,760 (click here to show other Interactions for entry)
Diseases:	Metabolic
Organism:	Mus musculus
Organism Model:	ApoE(-/-) KO mouse; Ldlr(-/-) KO mouse
Publication type:	article
Reference:	[PMID: 23823482]

Interaction Information:

Comment	Cold-induced conversion from white adipose tissue (WAT) into brown-like adipose tissue (BRITE) (=WAT-BRITE conversion), brown adipose tissue (BAT) activation, blood lipid profile, lipolysis, and cholesterol synthesis of ApoE-/- mice was investigated. A number of lipolysis-related genes, including fabp3, ucp1, elovl3, cpt1b, thea, cox7a1, gyk, pank1, pdk4, cox8b, idh3a, gys2, gpd2, acdav1, ndufab, acaa2, and pparg1b, were highly expressed in 4¬įC for 1 week or 4¬įC for 5 week inguinal WAT (iWAT).
Formal Description Interaction-ID: 109656	organism model ApoE KO mouse increases_expression of gene/protein GPD2 in inguinal WAT of Apoe (-/-) mice; following cold exposure 4¬įC for 1 week or 4¬įC for 5 week

Comment	Cold-induced conversion from white adipose tissue (WAT) into brown-like adipose tissue (BRITE) (=WAT-BRITE conversion), brown adipose tissue (BAT) activation, blood lipid profile, lipolysis, and cholesterol synthesis of ApoE-/- mice was investigated. A number of lipolysis-related genes, including fabp3, ucp1, elovl3, cpt1b, thea, cox7a1, gyk, pank1, pdk4, cox8b, idh3a, gys2, gpd2, acdav1, ndufab, acaa2, and pparg1b, were highly expressed in 4¬įC for 1 week or 4¬įC for 5 week inguinal WAT (iWAT).
Formal Description Interaction-ID: 109672	environment cold exposure increases_expression of gene/protein GPD2 in inguinal WAT of Apoe (-/-) mice; following cold exposure 4¬įC for 1 week or 4¬įC for 5 week

Comment	Cold-induced conversion from white adipose tissue (WAT) into brown-like adipose tissue (BRITE) (=WAT-BRITE conversion), brown adipose tissue (BAT) activation, blood lipid profile, lipolysis, and cholesterol synthesis of ApoE-/- mice was investigated. A number of lipolysis-related genes, including fabp3, ucp1, elovl3, cpt1b, thea, cox7a1, gyk, pank1, pdk4, cox8b, idh3a, gys2, gpd2, acdav1, ndufab, acaa2, and pparg1b, were highly expressed in 4¬įC for 1 week or 4¬įC for 5 week inguinal WAT (iWAT).
Formal Description Interaction-ID: 136859	gene/protein APOE affects_expression of gene/protein GPD2 in inguinal WAT of Apoe (-/-) mice; following cold exposure 4¬įC for 1 week or 4¬įC for 5 week
Drugbank entries	Show/Hide entries for APOE
Drugbank DB00062	Human Serum Albumin not specified APOE
Drugbank DB00064	Serum albumin iodonated not specified APOE
Drugbank DB00062	Human Serum Albumin not specified APOE
Drugbank DB00064	Serum albumin iodonated not specified APOE

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